Prakash Lab 12/12/24 Prakash Lab 12/12/24

Adaptive directional springs (ADS) and self-learning mechanical circuits

Manu Prakash, Vishal Prakash Patil, Ian Ho

LINK: www.freepatentsonline.com/y2024/0410436.html

Prakash Lab 11/20/24 Prakash Lab 11/20/24

Ice gliding diatoms establish record-low temperature limit for motility in a eukaryotic cell

Zhang, Q., Leng, H. T., Li, H., Arrigo, K. R., & Prakash, M. (2024). Ice gliding diatoms establish record-low temperature limit for motility in a eukaryotic cell. bioRxiv, 2024-11.

DOI: https://doi.org/10.1101/2024.11.18.624199

Prakash Lab 11/18/24 Prakash Lab 11/18/24

Inflation-induced motility for long-distance vertical migration

Larson, A. G., Chajwa, R., Li, H., & Prakash, M. (2024). Inflation-induced motility for long-distance vertical migration. Current Biology, 34(22), 5149-5163.

DOI: 10.1016/j.cub.2024.09.046

Prakash Lab 10/16/24 Prakash Lab 10/16/24

Escape motility of multicellular magnetotactic prokaryotes

Yang, X., Prakash, M., & Brumley, D. R. (2024). Escape motility of multicellular magnetotactic prokaryotes. Journal of the Royal Society Interface, 21(219), 20240310.

DOI: https://doi.org/10.1098/rsif.2024.0310

Prakash Lab 10/14/24 Prakash Lab 10/14/24

ESPressoscope: a small and powerful platform for in situ microscopy

Li, E., Saggiomo, V., Ouyang, W., Prakash, M., & Diederich, B. (2024). ESPressoscope: A small and powerful approach for in situ microscopy. Plos one, 19(10), e0306654.

DOI: https://doi.org/10.1371/journal.pone.0306654

Prakash Lab 10/11/24 Prakash Lab 10/11/24

Hidden Comet-Tails of Marine Snow Impede Ocean-based Carbon Sequestration

Chajwa, R., Flaum, E., Bidle, K. D., Van Mooy, B., & Prakash, M. (2024). Hidden comet tails of marine snow impede ocean-based carbon sequestration. Science, 386(6718), eadl5767.

DOI: https://doi.org/10.1126/science.adl5767

Prakash Lab 10/2/24 Prakash Lab 10/2/24

Single Cells Signal Non-self from Self via ‘XOR’ and ‘NOT EQUALS’ Logic in a Dimer of Dimers

An, R., & Prakash, M. (2024). Single Cells Signal Non-self from Self via'XOR'and'NOT EQUALS'Logic in a Dimer of Dimers. bioRxiv, 2024-10.

DOI: https://doi.org/10.1101/2024.10.01.616003

Prakash Lab 10/1/24 Prakash Lab 10/1/24

Creased ciliary flocks shape unfolding dynamics via information bottlenecks in an aneural animal

Brannon, C. M., & Prakash, M. (2024). Creased ciliary flocks shape unfolding dynamics via information bottlenecks in an aneural animal. bioRxiv, 2024-09.

DOI: https://doi.org/10.1101/2024.09.30.615941

Prakash Lab 9/24/24 Prakash Lab 9/24/24

Morphology-based classification of sickle cell disease and β-thalassemia using a low-cost automated microscope and machine learning

Shrestha, P., Lohse, H., Bhatla, C., McCartney, H., Alzaki, A., Sandhu, N., ... & Stoeber, B. (2024). Morphology-based classification of sickle cell disease and β-thalassemia using a low-cost automated microscope and machine learning. medRxiv, 2024-09.

DOI: https://doi.org/10.1101/2024.09.21.24314128

Prakash Lab 8/24/24 Prakash Lab 8/24/24

Biophysical limits of ultrafast cellular motility

Chang, R., & Prakash, M. (2024). Biophysical limits of ultrafast cellular motility. bioRxiv, 2024-08.

DOI: https://doi.org/10.1101/2024.08.22.609204

Prakash Lab 7/7/24 Prakash Lab 7/7/24

Split Luciferase Molecular Tension Sensors for Bioluminescent Readout of Mechanical Forces in Biological Systems

Zhong, B. L., Elliot, J. M., Wang, P., Li, H., Hall, R. N., Wang, B., Prakash, M., & Dunn, A. R. (2024). Split Luciferase Molecular Tension Sensors for Bioluminescent Readout of Mechanical Forces in Biological Systems. ACS sensors, 9(7), 3489-3495.

DOI: https://doi.org/10.1021/acssensors.3c02664

Prakash Lab 6/14/24 Prakash Lab 6/14/24

Flight-Scope: microscopy with microfluidics in microgravity

Wareing, T., Stokes, A., Crompton, K., Murphy, K., Dawson, J., Urgurluoglu, Y. F., Richardson, C., Li, H., Prakash, M., & Wollman, A. J. (2024). Flight-Scope: microscopy with microfluidics in microgravity. bioRxiv, 2024-06.

DOI: https://doi.org/10.1101/2024.06.12.598447

Prakash Lab 6/11/24 Prakash Lab 6/11/24

A genetic and microscopy toolkit for manipulating and monitoring regeneration in Macrostomum lignano

Hall, R. N., Li, H., Chai, C., Vermeulen, S., Bigasin, R. R., Song, E. S., Sarkar, S.R., Gibson, J., Prakash, M., Fire, A.Z, & Wang, B. (2024). A genetic and microscopy toolkit for manipulating and monitoring regeneration in Macrostomum lignano. Cell Reports, 43(11).

DOI: 10.1016/j.celrep.2024.114892

Prakash Lab 6/11/24 Prakash Lab 6/11/24

Rapid, antibiotic incubation-free determination of tuberculosis drug resistance using machine learning and Raman spectroscopy

Ogunlade, B., Tadesse, L. F., Li, H., Vu, N., Banaei, N., Barczak, A. K., ... & Dionne, J. A. (2024). Rapid, antibiotic incubation-free determination of tuberculosis drug resistance using machine learning and Raman spectroscopy. Proceedings of the National Academy of Sciences, 121(25), e2315670121.

DOI: https://doi.org/10.1073/pnas.2315670121

Prakash Lab 6/10/24 Prakash Lab 6/10/24

Droplet tilings in precessive fields: hysteresis, elastic defects, and annealing

Molina, A., & Prakash, M. (2024). Droplet tilings in precessive fields: hysteresis, elastic defects, and annealing. Soft Matter, 20(34), 6730-6741.

DOI: https://doi.org/10.1039/D4SM00475B

Prakash Lab 6/7/24 Prakash Lab 6/7/24

Curved crease origami and topological singularities enable hyperextensibility of L. olor

Flaum, E., & Prakash, M. (2024). Curved crease origami and topological singularities enable hyperextensibility of L. olor. Science, 384(6700), eadk5511.

DOI: https://doi.org/10.1126/science.adk5511

Prakash Lab 5/10/24 Prakash Lab 5/10/24

Coupling and uncoupling of midline morphogenesis and cell flow in amniote gastrulation

Asai, R., Prakash, V. N., Sinha, S., Prakash, M., & Mikawa, T. (2024). Coupling and uncoupling of midline morphogenesis and cell flow in amniote gastrulation. Elife, 12, RP89948.

DOI: https://doi.org/10.7554/eLife.89948.3

Prakash Lab 2/21/24 Prakash Lab 2/21/24

Algorithmic construction of topologically complex biomineral lattices via cellular syncytia

Vyas, P., Brannon, C. M., Formery, L., Lowe, C., & Prakash, M. (2024). Algorithmic construction of topologically complex biomineral lattices via cellular syncytia. bioRxiv, 2024-02.

DOI: https://doi.org/10.1101/2024.02.20.580924

Prakash Lab 2/21/24 Prakash Lab 2/21/24

Energetics of the Microsporidian Polar Tube Invasion Machinery

Chang, R., Davydov, A., Jaroenlak, P., Budaitis, B., Ekiert, D. C., Bhabha, G., & Prakash, M. (2024). Energetics of the microsporidian polar tube invasion machinery. Elife, 12, RP86638.

DOI: https://doi.org/10.1101/2023.01.17.524456

Prakash Lab 1/22/24 Prakash Lab 1/22/24

Co-axial plunger based home molecular diagnostics kit

Inventors: Manu Prakash, Anesta Kothari, Adam Larson, Shailabh Kumar, Hazel Soto-Montoya

Prakash Lab 11/30/23 Prakash Lab 11/30/23

Agave sisalana: towards distributed manufacturing of absorbent media for menstrual pads in semi-arid regions

Molina, A., Kothari, A., Odundo, A., & Prakash, M. (2023). Agave sisalana: towards distributed manufacturing of absorbent media for menstrual pads in semi-arid regions. Communications Engineering, 2(1), 81.

DOI: https://doi.org/10.1038/s44172-023-00130-y

Prakash Lab 10/20/23 Prakash Lab 10/20/23

Mechanopathology of biofilm-like Mycobacterium tuberculosis cords

Mishra, R., Hannebelle, M., Patil, V. P., Dubois, A., Garcia-Mouton, C., Kirsch, G. M., ... & Thacker, V. V. (2023). Mechanopathology of biofilm-like Mycobacterium tuberculosis cords. Cell, 186(23), 5135-5150.

DOI: https://doi.org/10.1016/j.cell.2023.09.016

Prakash Lab 10/4/23 Prakash Lab 10/4/23

Topological damping in an ultrafast giant cell

Chang, R., & Prakash, M. (2023). Topological damping in an ultrafast giant cell. Proceedings of the National Academy of Sciences, 120(41), e2303940120.

DOI: https://doi.org/10.1073/pnas.2303940120

Prakash Lab 9/13/23 Prakash Lab 9/13/23

Thermotaxis in an apolar, non-neuronal animal

Zhong, G., Kroo, L., & Prakash, M. (2023). Thermotaxis in an apolar, non-neuronal animal. Journal of the Royal Society Interface, 20(206), 20230279.

DOI: https://doi.org/10.1098/rsif.2023.0279

Prakash Lab 7/28/23 Prakash Lab 7/28/23

Culture-Independent Multiplexed Detection of Drug-Resistant Bacteria Using Surface-Enhanced Raman Scattering

Dai, T., Xiao, Z., Shan, D., Moreno, A., Li, H., Prakash, M., ... & Rao, J. (2023). Culture-Independent Multiplexed Detection of Drug-Resistant Bacteria Using Surface-Enhanced Raman Scattering. ACS sensors, 8(8), 3264-3271.

DOI: https://doi.org/10.1021/acssensors.3c01345

Prakash Lab 7/5/23 Prakash Lab 7/5/23

Emergent programmable behavior and chaos in dynamically driven active filaments

Krishnamurthy, D., & Prakash, M. (2023). Emergent programmable behavior and chaos in dynamically driven active filaments. Proceedings of the National Academy of Sciences, 120(28), e2304981120.

DOI: https://doi.org/10.1073/pnas.2304981120

Prakash Lab 5/21/23 Prakash Lab 5/21/23

Active dislocations and topological traps govern dynamics of spiraling filamentous cyanobacteria

Gong, X., & Prakash, M. (2023). Active dislocations and topological traps govern dynamics of spiraling filamentous cyanobacteria. arXiv preprint arXiv:2305.12572.

DOI: https://doi.org/10.48550/arXiv.2305.12572

Prakash Lab 5/2/23 Prakash Lab 5/2/23

MultiSero: An Open-Source Multiplex-ELISA Platform for Measuring Antibody Responses to Infection

Byrum, J. R., Waltari, E., Janson, O., Guo, S. M., Folkesson, J., Chhun, B. B., Vinden, J., Ivanov, I. E., Forst, M. L., Li, H., Larson, A. G., Blackmon, L., Liu, Z., Wu, W., Ahyong, V., Tato, C. M., McCutcheon, K. M., Hoh, R., Kelly, J. D., Martin, J. N., Peluso, M. J. Henrich, T. J., Deeks, S. G., Prakash, M., Greenhouse, B., Mehta, S. B., Pak, J. E. (2023). MultiSero: An Open-Source Multiplex-ELISA Platform for Measuring Antibody Responses to Infection. Pathogens, 12(5), 671.

DOI: https://doi.org/10.3390/pathogens12050671

Prakash Lab 4/27/23 Prakash Lab 4/27/23

A Spectral Imaging Platform For Infectious Disease Diagnosis

Hongquan Li, Manu Prakash

Link: https://patents.google.com/patent/US20220206007A1/en

Prakash Lab 4/27/23 Prakash Lab 4/27/23

Paperfuge: An integrated paper-based centrifugation and microfluidics platform for low-cost diagnostics

Manu Prakash, Mohammed Saad Bhamla, James Stanley Cybulski, Chew Chai, Aanchal Johri, Brandon Benson

Link: https://patents.google.com/patent/US11331665B2/en

Prakash Lab 4/20/23 Prakash Lab 4/20/23

Inkwell: Design and Validation of a Low-Cost Open Electricity-Free 3D Printed Device for Automated Thin Smearing of Whole Blood

Nowak, J., Kothari, A., Li, H., Pannu, J., Algazi, D., & Prakash, M. (2023). Inkwell: Design and validation of a low-cost open electricity-free 3d printed device for automated thin smearing of whole blood. arXiv preprint arXiv:2304.10200.

DOI: https://doi.org/10.48550/arXiv.2304.10200

Prakash Lab 4/18/23 Prakash Lab 4/18/23

Self-learning mechanical circuits

Patil, V. P., Ho, I., & Prakash, M. (2023). Self-learning mechanical circuits. arXiv preprint arXiv:2304.08711.

DOI: https://doi.org/10.48550/arXiv.2304.08711

Prakash Lab 3/6/23 Prakash Lab 3/6/23

Active foam: the adaptive mechanics of 2D air–liquid foam under cyclic inflation

Kroo, L. A., Bull, M. S., & Prakash, M. (2023). Active foam: the adaptive mechanics of 2D air–liquid foam under cyclic inflation. Soft Matter, 19(14), 2539-2553.

DOI: https://doi.org/10.1039/D3SM00019B

Prakash Lab 3/5/23 Prakash Lab 3/5/23

Effect of age on wingbeat frequency of Aedes aegypti and potential application for age estimation of mosquitoes

Park, D., Bowles, J., Norrid, K., Dobson, F. S., Abebe, A., Narayanan, H. V., ... & Zohdy, S. (2023). Effect of age on wingbeat frequency of Aedes aegypti and potential application for age estimation of mosquitoes. Medical and Veterinary Entomology, 37(3), 491-498.

DOI: https://doi.org/10.1111/mve.12647

Prakash Lab 2/8/23 Prakash Lab 2/8/23

Active sinking particles: sessile suspension feeders significantly alter the flow and transport to sinking aggregates

Krishnamurthy, D., Pepper, R., & Prakash, M. (2023). Active sinking particles: sessile suspension feeders significantly alter the flow and transport to sinking aggregates. Journal of the Royal Society Interface, 20(199), 20220537.

DOI: https://doi.org/10.1098/rsif.2022.0537

Prakash Lab 12/3/22 Prakash Lab 12/3/22

Eye Detection from Face Images covered in Face-masks using HAAR features

Akshay, S., Prakash, M., & Das, K. H. (2022, December). Eye Detection from Face Images covered in Face-masks using HAAR features. In 2022 IEEE 7th International Conference on Recent Advances and Innovations in Engineering (ICRAIE) (Vol. 7, pp. 160-165). IEEE.

DOI: https://doi.org/10.1109/ICRAIE56454.2022.10054252

Prakash Lab 10/17/22 Prakash Lab 10/17/22

ABC: A Deep learning Iris Recogniser for Secure Borders and Automated Border Crossing

Akshay, S., Kt, H. D., & Prakash, M. (2022, October). ABC: A Deep learning Iris Recogniser for Secure Borders and Automated Border Crossing. In 2022 IEEE 2nd Mysore Sub Section International Conference (MysuruCon) (pp. 1-6). IEEE.

DOI: https://doi.org/10.1109/MysuruCon55714.2022.9972402

Prakash Lab 8/16/22 Prakash Lab 8/16/22

Plankton Planet: A frugal, cooperative measure of aquatic life at the planetary scale

de Vargas, C., Le Bescot, N., Pollina, T., Henry, N., Romac, S., Colin, S., Haëntjens, N., Carmichael, M., Berger, C., Guen, D. L., Decelle, J., Mahé, F., Poulain, J., Malpot, E., Beaumont, C., Hardy, M., Guiffant, D., Probert, I., Gruber, D. F., Allen, A. E., Gorsky, G., Follows, M. J., Pochon, X., Troublé, R., Cael, B. B., Lombard, F., Boss, E., Prakash, M., & Plankton Planet core team. (2022). Plankton Planet: A frugal, cooperative measure of aquatic life at the planetary scale. Frontiers in Marine Science, 9, 936972.

DOI: https://doi.org/10.3389/fmars.2022.936972

Prakash Lab 7/21/22 Prakash Lab 7/21/22

PlanktoScope: Affordable Modular Quantitative Imaging Platform for Citizen Oceanography

Pollina, T., Larson, A. G., Lombard, F., Li, H., Le Guen, D., Colin, S., de Vargas, C., & Prakash, M. (2022). PlanktoScope: affordable modular quantitative imaging platform for citizen oceanography. Frontiers in Marine Science, 9, 949428.

DOI: https://doi.org/10.3389/fmars.2022.949428

Prakash Lab 7/4/22 Prakash Lab 7/4/22

Basin-Scale Underway Quantitative Survey of Surface Microplankton Using Affordable Collection and Imaging Tools Deployed From Tara

Mériguet, Z., Oddone, A., Le Guen, D., Pollina, T., Bazile, R., Moulin, C., Troublé, M., Prakash, M., de Vargas, C., Lombard, F. (2022). Basin-scale underway quantitative survey of surface microplankton using affordable collection and imaging tools deployed from Tara. Frontiers in Marine Science, 9, 916025.

DOI: https://doi.org/10.3389/fmars.2022.916025

Prakash Lab 6/28/22 Prakash Lab 6/28/22

A freely suspended robotic swimmer propelled by viscoelastic normal stresses

Kroo, L. A., Binagia, J. P., Eckman, N., Prakash, M., & Shaqfeh, E. S. (2022). A freely suspended robotic swimmer propelled by viscoelastic normal stresses. Journal of Fluid Mechanics, 944, A20.

DOI: https://doi.org/10.1017/jfm.2022.485

Prakash Lab 4/19/22 Prakash Lab 4/19/22

Low cost centrifugal melt spinning for distributed manufacturing of non-woven media

Molina, A., Vyas, P., Khlystov, N., Kumar, S., Kothari, A., Deriso, D., Liu, Z., Banavar, S., Flaum, E., & Prakash, M. (2022). Low cost centrifugal melt spinning for distributed manufacturing of non-woven media. Plos one, 17(4), e0264933.

DOI: https://doi.org/10.1371/journal.pone.0264933